Mazdutide

Mazdutide is a long-acting synthetic oxyntomodulin (OXM) analog and a dual co-agonist of the glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR). By simultaneously activating two incretin signaling pathways, Mazdutide achieves superior weight reduction and glycemic control compared to single-target GLP-1 agonists through potent appetite suppression, delayed gastric emptying, and additional energy expenditure enhancement.