Retatrutide

Triple-target peptide API revolutionizing metabolic disease treatment. Simultaneous activation of GLP-1R, GIPR, and GCGR delivers unprecedented efficacy in glucose control and weight management.

Retatrutide (development code LY3437943) is a first-in-class triple hormone receptor agonist peptide developed by Eli Lilly and Company, designed for the treatment of obesity and type 2 diabetes. It simultaneously activates three distinct metabolic hormone receptors: glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon (GCG), delivering unprecedented synergistic effects on body weight reduction, glycemic control, and metabolic health.

CAS 2381089-83-2
Molecular Formula C₂₂₃H₃₄₈N₆₈O₇₅
Molecular Weight 4775.42 g/mol
Category GLP-1 & Incretin Metabolic Peptides
Purity >=99% (HPLC)
Status GMP-compliant, FDA-ready
Applications Severe obesity, refractory diabetes, metabolic syndrome
CAS

2381089-83-2

Applications

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