Nonapeptide-1
Skin whitening peptide for melanin inhibition. Synthetic melanocyte-stimulating hormone antagonist reducing tyrosinase activity and melanin production for brightening and even skin tone formulations.
Nonapeptide-1, also known by the trade name Melanostatine, is a pioneering synthetic nonapeptide (nine amino acid peptide) specifically engineered for skin brightening and depigmentation. It represents a breakthrough in cosmetic science as the first peptide-based melanogenesis inhibitor that operates through receptor-level competition rather than cytotoxicity, offering a safe and gentle alternative to traditional whitening agents such as hydroquinone, kojic acid, and arbutin.
| Parameter | Specification |
| CAS | 158563-45-2 |
| Molecular Formula | C₆₁H₈₇N₁₅O₉S |
| Molecular Weight | 1206.51 g/mol |
| Category | Whitening |
| Purity | ≥99% |
| Status | Cosmetic-grade, INCI compliant |
| Applications | Skin whitening, melanin inhibition, brightening, hyperpigmentation |
| CAS | 158563-45-2 |
|---|---|
| Applications | Melanin Inhibitor, Post-treatment Care, Sensitive Skin, Whitening Peptide |




