Acetyl Hexapeptide-8 (Argireline)
Botulinum toxin-like peptide for expression line reduction. Hexapeptide inhibiting SNARE complex formation to reduce muscle contraction intensity, smoothing dynamic wrinkles in anti-aging formulations.
Acetyl Hexapeptide-8, widely recognized by the trade name Argireline, is a synthetic cosmetic peptide and the world’s first anti-wrinkle hexapeptide with a Botox-like mechanism of action. Developed by Lipotec (Barcelona, Spain) and first introduced to the cosmetic industry in 2002, it has since become one of the most extensively studied and widely used neuropeptides in premium skincare formulations globally. Its INCI name is Acetyl Hexapeptide-8, and it is also known as Acetyl Hexapeptide-3 in earlier literature.
| Parameter | Specification |
| CAS | 616204-22-9 |
| Molecular Formula | C₃₄H₆₀N₁₄O₁₂S |
| Molecular Weight | 888.99 g/mol |
| Category | Anti-wrinkle |
| Purity | ≥99% |
| Status | Cosmetic-grade, INCI compliant |
| Applications | Expression line reduction, forehead wrinkles, crow’s feet, anti-aging skincare |
| CAS | 616204-22-9 |
|---|---|
| Applications | Anti-aging Creams, Firming Products, Post-treatment Care, Wrinkle Reduction |




