Pentapeptide-18
Collagen promotion and elasticity enhancement peptide. Pentapeptide stimulating collagen synthesis and improving skin elasticity through TGF-β signaling pathway activation.
Pentapeptide-18 is a high-performance biomimetic peptide designed for advanced anti-wrinkle and expression line reduction applications. Composed of five amino acids (Tyr-D-Ala-Gly-Phe-Leu) with a molecular weight of approximately 569.7 g/mol, this innovative peptide targets the neuromuscular junction by modulating synaptic vesicle fusion, thereby reducing acetylcholine release and attenuating muscle contraction intensity. Unlike conventional neurotoxin-inspired peptides, Pentapeptide-18 operates through a unique calcium-dependent mechanism that softens facial expression lines without compromising natural facial movement, making it one of the most elegant and effective peptide-based wrinkle relaxants in the cosmetic industry.
| Parameter | Specification |
| CAS | 64963-01-5 |
| Molecular Formula | C₂₉H₄₅N₅O₇ |
| Molecular Weight | 575.71 g/mol |
| Category | Anti-wrinkle |
| Purity | ≥99% |
| Status | Cosmetic-grade, INCI compliant |
| Applications | Collagen promotion, elasticity enhancement, anti-wrinkle, anti-aging |
| CAS | 64963-01-5 |
|---|---|
| Applications | Anti-aging Skincare, Post-treatment Care, Sensitive Skin Care, Wrinkle Smoothing |




